Adjuvant Whole-Brain Radiotherapy: End of an Era?

New details from a clinical trial showing negative effects of whole-brain radiotherapy combined with stereotactic radiosurgery (SRS) in the treatment of brain cancer — and no improvement in overall survival — further call into question the use of the approach in the treatment of patients with one to three brain metastases. “We think this study represents the end of an era in neuro-oncology,” presenter Anthony L. Asher, MD, a neurosurgeon with the Department of Neurological Surgery at Carolina Neurosurgery and Spine Associates, Charlotte, North Carolina, told Medscape Medical News.