Gene therapy could prevent radiotherapy side effects, improve breast reconstruction, study suggests

A new virus-based gene therapy could protect healthy tissue from the effects of radiotherapy and improve breast reconstruction surgery, a study with lab rats suggests. The therapy delivers copies of stress-limiting proteins into healthy tissues, preventing the side effects that sometimes appear months or years after cancer radiotherapy treatment, which limit the effectiveness of breast reconstruction surgery. The therapy not only protected the transplanted tissue but also improved the destruction of tumour cells by radiotherapy, a team from The Institute of Cancer Research, London, showed.
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