Hadron minibeams: a less toxic treatment

Minibeam radiotherapy uses an array of high-dose, sub-millimetre-sized radiation beams – which gradually broaden and merge – to spare normal tissues while enabling delivery of high doses to target tumours. The premise is that the smaller the treatment field, the higher the tolerance of healthy tissue. Indeed, studies performed using synchrotron radiation have shown that healthy tissue can withstand doses of more than 100 Gy if the field size is small enough.