Intensive, multi-agent regimen may prolong EFS in metastatic rhabdomyosarcoma

Pediatric and young adult patients with metastatic rhabdomyosarcoma who had no more than one Oberlin risk factor experienced favorable EFS outcomes with intensive multi-agent therapy, according to study results from the Children’s Oncology Group. However, patients with two or more Oberlin risk factors experienced a poor prognosis even with the combined-therapy regimen, which included dose-compressed chemotherapy and radiation, results showed.