Research shows potential way to counteract glioblastoma growth by blocking PPARα receptor

In a new study published in the Journal of Cellular Physiology, researchers examined the effects of a new inhibitor, AA452, of a transcription factor, PPARα, known to be involved in the control of energetic metabolism. The result obtained in this study indicates that blocking PPARα in glioblastoma cells affected a strong decrease of cell proliferation and migration, as well as induced a major sensitivity to radiotherapy.
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